Coronavirus antiviral medicine
Lopinavir/Ritonavir tablets is actively used in the treatment of children and pregnant women due to lower health risks. And Recombinant interferon beta-1b shows the best results in the fight against the Chinese coronavirus pathogen. Chloroquine and Gidroksihlorohina counterparts in composition and principle of action, different manufacturer, price, release form. Azithromycin acts as a bacteriostatic agent, it is used in case of complications in combination with antimalarial drugs.
Potentially suitable medications for the treatment of coronavirus. These are antiviral drugs that act on retroviruses, such as the human immunodeficiency virus (HIV). Reverse transcriptase inhibitors block the enzyme reverse transcriptase, which is necessary for HIV replication. Nucleoside reverse transcriptase inhibitors initiated the treatment of HIV infection. The drugs Retrovir and Timazid were used until the mid-90s, then several more drugs of this group appeared. Studies of the structure of reverse transcriptase made it possible to create new classes of drugs that do not belong to nucleosides, which are called non-nucleoside reverse transcriptase inhibitors.
Coronavirus antiviral medications in the symptomatic treatment of coronavirus, the main role is played by an effective antiviral drug used as prescribed by a doctor. They are used to prevent infection with coronavirus infection, as well as reduce respiratory signs of the disease and prevent the development of dangerous complications.
Protease inhibitors lopinavir + ritonavir have activity against coronavirus in vitro. In severe atypical pneumonia caused by the SARS virus, this combination reduced the risk of respiratory distress syndrome and death. Ritonavir (Norvir) is one of the most complex inhibitors and was developed for the treatment of HIV infection. Its own antiviral activity is rarely used, but it is used in low doses as an enhancer of other protease inhibitors.
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Can antibiotics be used for coronavirus and do they help?
Antibiotics are prescribed only for complications, if a bacterial secondary infection develops. Severe cases of the disease are considered complicated, and such patients are subject to hospitalization, where treatment is carried out.
Why can't I take antibiotics for prevention?
Because Coronavirus antiviral tablets do not have any preventive effect, and their irrational use only reduces the human immune system, suppresses the beneficial intestinal microflora. The gastrointestinal tract is an important part of the immune system. The gut is a human immune organ, since 25% of its mucosa is immunologically active. And the microflora has an immunomodulatory effect, since it supports the synthesis of immunoglobulins, stimulates the production of B-lymphocytes, stimulates the immune response, and increases the number of T-helpers.
Do I need antibiotics for uncomplicated forms and why do antibiotics not help with coronavirus?
Because they do not affect (do not kill) the virus.
The medicine Chloroquine has recently been actively used in the antiviral medicine for coronavirus infection with the development of viral pneumonia with complications. According to its composition, it belongs to the group of 4-aminoquinoline derivatives. It guarantees several therapeutic effects at once – immunosuppressive, anti-inflammatory, antiarrhythmic, antimalarial, and Antiprotozoal. The active ingredient is chloroquine phosphate. Product form – powder, tablets, solution for injection. In the case of this disease, it suppresses an overly active immune response, thereby preventing a cytokine "storm". For use, it is mandatory to monitor the doctor with the delivery of tests, ECG. Prevention is not recommended, Chloroquine is used for treatment. If the inflammatory process due to the development of COVID-19 provokes the attraction of a huge number of lymphocytes in the lungs, the immune response increases several times. This threatens to destroy the lungs, damage other organs. The immunosuppressor Chloroquine can prevent this outcome.
The effectiveness of such an antibiotic in the treatment of COVID-19 was established by medical experts in France. Moreover, the best results were obtained when this drug was combined with the antimalarial drugs listed above. The active ingredient in the composition is a semi – synthetic antibiotic from the group of azalides with the same name. Once in the body, it disrupts the vital activity of bacterial cells. There are several forms of release – tablets, powder, capsules, lyophilizate. The bacteriostatic drug is prescribed only by a doctor's prescription, as it has contraindications and side effects. In comparison with low toxicity, Azithromycin is used in the treatment of infections of the ENT organs, upper or lower respiratory tract, urogenital tract, and skin.